A God-given sign of faith, not honored as such, carries notable risk with its dishonor. It's not because the substance of the sign (the elements) was violated, but because of the attitude betrayed toward what is conveyed by them. There is no implication in such punishment that necessitates that it entail an affront to some special presence, or gracious virtue. Guilt accrues over simple bread and wine simply because one who is disrespectful of the sign is disdainful of the thing signified by it. One needs to discern this truth when participating in the Supper.
There is no biblical rule that tells us how often to celebrate the Lord's Supper. The implication in the NT, it seems to me, is that it was practiced often, maybe even at every worship meeting of the first congregations. Nonetheless, I think that if God would have had in mind the sacramental effect that has been saddled on the practice of Communion throughout most of church history, the Spirit would have commanded it less nebulously than "as oft as you eat and drink." No, the spooky necessity attached to the feast is on the back of man rather than the Son of Man.
The celebration does nothing to forgive sin, tap into the blessings God has provided in Christ, or mysteriously bind us together in the one bread and one body of Christ--it bears no sacramental necessity at all. Jesus inaugurated the meal with the disciples to serve as a memorial until he could eat and drink it again with them in the kingdom of God. It is simply a God-given way of remembering the means by which we stand before God accepted, and to proclaim our faith that Christ died for our sins, rose for our justification, and is returning for the consummation of his eternal kingdom.
As such the ordinance should not be entered upon callously. One should examine himself before participating and ensure within his own mind that he participates with Christ in view, in a way that honors what Jesus did and taught. That means not eating to satisfy physical hunger or appetite; nor eating self-centeredly, ignoring the body Christ bled and died for. To participate in an manner unworthy of Christ is to eat and drink judgment upon oneself.