The further we proceed into the prophetic future, the more speculative are my interpretations. Generally, after doing some double checking, I go with whatever strikes "my gut" after reading the descriptions in the text. I am satisfied that I am at least in the ballpark concerning what these things mean. They weren't meant to be all that mysterious after all.
Either just before or just after the Rapture, the Antichrist, as leader of the 10 nations, will seal a treaty between his alliance and Israel. Although the details of the pact are not known at this time, it will have a treaty period of seven years, and it can be inferred that it will allow Israel to rebuild the Temple and attempt to reinstate the OT sacrificial system. This will signal the advent of Daniel's 70th week and the concluding of God's promises to him concerning the people of Israel and Jerusalem. The seventh seal has been broken.
At that time, Enoch and Elijah will begin prophesying in Jerusalem, speaking a message that must be antagonistic toward the world, toward unbelief in Israel, and toward the Antichrist. Though no one in the world appreciates their message, no one can do anything to stop them. While they are prophesying, 144,000 sealed and protected Messianic Jews are present (probably in Israel) having whatever redemptive affect they may have on the Jewish people.
Shortly thereafter, fiery hail will fall upon the earth (probably the aftereffect of the volcanic cataclysm which was the sixth seal) and a third of earth's vegetation will be lost. The first trumpet has sounded.
Then, an asteroid will strike one of earth's oceans, polluting a third of the seas, killing a third of the life therein, and sinking a third of the ships sailing the seas (perhaps as a result of tsunamis). The second trumpet has sounded.
On the heels of that asteroid strike, another will fall, maybe in a lake (like the Great Lakes) or upon land, but definitely not in the ocean, and its aftereffect will be the pollution of a third of the fresh water on Earth. Note: I do not see the megastar presented as the proximate cause of this catastrophe as necessarily an angel, even though specified stars in the Apocalypse generally are. The third trumpet has sounded.
Probably as a result of the ejecta of these asteroid strikes, a third of the light of the sun, moon and stars will be darkened. The fourth trumpet has sounded.
Then a tremendously annoying but not deadly disease will spread throughout the earth. Its tortuous symptoms will last five months. I doubt the inhabitants of the earth will suspect the demonic origin of the epidemic, anymore than they suspect that kind of thing in disease now. The fifth trumpet has sounded and the demons have been loosed upon earth.
Not long afterward (nothing could be since we're only dealing with a total of 3 1/2 years in this entire section), a third of the human race alive at that time will be overcome by what appears to be pyroclastic flows or the volcanic aftereffects of the cataclysm of seal six and/or the asteroids of trumpets two and three. Ground Zero for this event will be the Euphrates River, but the spread of the effect is not detailed (although I speculate it would be easterly toward the populations of India and China). As with trumpet five, I doubt the inhabitants of the earth will suspect the demonic origin of the catastrophe. The sixth trumpet has sounded.
For whatever reason (having undergone what is described above may be reason enough), Egypt will rebel against the Antichrist and his alliance. The Antichrist will lead a response of such cold-blooded, lethal and overwhelming force that the heart of any other potential rebel will find itself without resolve. Whether through biological, chemical, or nuclear means, the wound of Egypt's (one of the seven heads) rebellion is staunched, the Antichrist is strengthened, and the world amazed and awe-struck. Egypt will suffer the aftereffects for a generation into the reign of Christ.
As the Antichrist turns back toward his base in Turkey, he will pass through Israel and stop at Jerusalem. There he kills Enoch and Elijah and leaves their bodies dead in the street, though God raises them back to life and then to heaven. The 144,000 appear to go to heaven with them. A strong earthquake will rock the city, but won't stop the Antichrist from confiscating the Temple, putting an end to Israeli plans to reinstate the OT sacrificial system.
Nothing is left for the inhabitants of earth at that time but the duress of God's wrath.
Yet to Come... the second half of the Tibulation